| October 1, 2022 | ||
| Bidco United | 15:00 | Nzoia Sugar |
| KCB | 15:00 | Kariobangi Sharks |
| Talanta | 15:00 | Fortune Sacco |
| Gor Mahia | 15:00 | Ulinzi Stars |
| October 2, 2022 | ||
| APS Bomet | 15:00 | Nairobi City Stars |
| Homeboyz | 15:00 | Leopards |
| Police | 15:00 | Bandari |
| Tusker | 15:00 | Posta Rangers |
| Wazito | 15:00 | Sofapaka |
| October 7, 2022 | ||
| Kariobangi Sharks | 15:00 | Homeboyz |
| Sofapaka | 15:00 | Bidco United |
| October 8, 2022 | ||
| Nairobi City Stars | 15:00 | Gor Mahia |
| Ulinzi Stars | 15:00 | APS Bomet |
| Posta Rangers | 15:00 | Talanta |
| Leopards | 15:00 | Tusker |
| Fortune Sacco | 15:00 | Police |
| Nzoia Sugar | 15:00 | KCB |
| Bandari | 15:00 | Wazito |
