| March 9, 2022 | ||
| Ulinzi Stars | 16:00 | Leopards |
| March 26, 2022 | ||
| Ulinzi Stars | 16:00 | Sofapaka |
| May 14, 2022 | ||
| Leopards | 15:00 | Kariobangi Sharks |
| Talanta | 15:00 | Gor Mahia |
| May 15, 2022 | ||
| Police | 15:00 | Mathare United |
| May 21, 2022 | ||
| Posta Rangers | 15:00 | Sofapaka |
| Mathare United | 15:00 | Wazito |
| KCB | 15:00 | Nairobi City Stars |
| Leopards | 15:00 | Talanta |
| Gor Mahia | 15:00 | Homeboyz |
| Bidco United | 15:00 | Police |
| May 22, 2022 | ||
| Kariobangi Sharks | 15:00 | Bandari |
| Vihiga Bullets | 15:00 | Ulinzi Stars |
| Tusker | 15:00 | Nzoia Sugar |
| May 28, 2022 | ||
| Nairobi City Stars | 13:00 | Gor Mahia |
| Ulinzi Stars | 15:00 | Bandari |
| Police | 15:00 | Posta Rangers |
| Sofapaka | 15:00 | Vihiga Bullets |
| Mathare United | 15:00 | Tusker |
